Under anesthesia

November 19, 2010 Research Center of Surgery named after Academician BV Petrovsky, Russian Academy of Medical Sciences conducted the fourth international conference on "Russian School of colorectal surgery." This will be a unique event, to participate in which will come top 500 colorectal and endoscopic surgery of the CIS countries, USA, Korea, Japan, China, etc.

The central theme of the upcoming brand viagra online conference - the present value of less invasive methods of surgical treatment of colon cancer.

During the meeting, scientists can observe the work of surgeons at two operating rooms, where they will undergo surgery using the latest techniques and technologies for treating this type of disease. Conference participants from the floor will be able generic viagra to ask doctors questions and get answers to them.

The purpose of the conference "Russian School of colorectal surgery" - learn from the experience and technology of colorectal surgery at the leading domestic and foreign experts. At the moment our country - among the laggards in this area.

About adhesive disease of peritoneum (SBB) annually in the brand name levitra surgical wards treated 1% of the previously operated patients, intestinal obstruction occurs in 50-75% of patients with PRSP and its conservative treatment is ineffective. After surgery for abdominal adhesions relapses of the disease are 32-71% mortality in adhesive intestinal obstruction in the range 13-55%, reliable means of preventing postoperative adhesions of the abdominal cavity (SPBP) to date are under development [2, 4 , 7, 11, 12].

Most authors are unanimous that the main etiopathogenetic factor in the disease is damage to the peritoneal mesothelium and inflammation with a predominance of its proliferative phase [1, 8, 13].

Many surgical diseases are accompanied by marked changes in the immune system, characterized as a state of secondary immunodeficiency. This is facilitated by a complex pathological factors underlying disease, stress, pain management, surgical trauma [6]. Investigation of immune status and attempts to correct for surgical patients showed that the use of immunomodulators in complex of modern methods of treatment promotes the elimination of postoperative complications, speeds up the healing of tissues, reduces the rehabilitation of patients after surgery [9].

Leading role in the induction of inflammation are polymorphonuclear leukocytes. They migrate cialis without prescription from the bloodstream into the tissues and carry out their protective functions. Products stimulated neutrophils affect the activity of macrophages, lymphocytes, platelets cause degranulation of mast cells, activate the complement system, blood coagulation, fibrinolysis in the area of traumatic injury of the peritoneum [3, 10]. In modern literature there is no unambiguous data on the status of immunity and nonspecific resistance factors in the PRSP.

Accordingly, the purpose of our study was to investigate the dynamic changes of factors of nonspecific resistance of the organism in experimental SPBP.

Experiments were conducted on healthy adult male rats of Wistar, weighing 250-300 g, contained on a standard diet of food and drink in a vivarium CSMU. Studies carried out in compliance with the principles set forth in the Convention for the Protection of Vertebrate Animals used for experimental and other purposes (Strasbourg, France, 1986).

In sterile conditions, under anesthesia rometarovym simulated SPBP. After a median incision was performed laparotomic hydraulic dissection abdominal ventral wall with subsequent excision of an area of 1 x 1 cm and 1 cm away from the edge of the median wound. Caecum been scarification on the entire generic levitra surface until the "bloody dew."

Animals were removed from the experiment by an overdose of anesthesia at 3, 7 and 14 days. Evaluated morphological changes in the abdominal cavity using a visual-descriptive method and the estimation of SPBP method of semantic differential. Bodies involved in SPBP were removed from cadavers were fixed in 10% neutral formalin with subsequent manufacturing of paraffin sections and hematoxylin-eosin, Pikra-Sirius red and Mallory.

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